Locomotor Ataxia

Locomotor Ataxia Complicating Labour

is accurately known as those bearing upon the nervous complications of pregnancy and parturition. On these grounds I have deemed it of sufficient importance to place on record the following case, although, obstetrically considered in the strictest sense of that word, it presented no special attraction:? J. B., primipara, the subject of this note, was a patient in the Royal Maternity Hospital du...

Locomotor patterns in cerebellar ataxia.

Several studies have demonstrated how cerebellar ataxia (CA) affects gait, resulting in deficits in multijoint coordination and stability. Nevertheless, how lesions of cerebellum influence the locomotor muscle pattern generation is still unclear. To better understand the effects of CA on locomotor output, here we investigated the idiosyncratic features of the spatiotemporal structure of leg mus...

A Surgical Treatment of Locomotor Ataxia

Spinocerebellar ataxia type 13 mutant potassium channel alters neuronal excitability and causes locomotor deficits in zebrafish.

Whether changes in neuronal excitability can cause neurodegenerative disease in the absence of other factors such as protein aggregation is unknown. Mutations in the Kv3.3 voltage-gated K(+) channel cause spinocerebellar ataxia type 13 (SCA13), a human autosomal-dominant disease characterized by locomotor impairment and the death of cerebellar neurons. Kv3.3 channels facilitate repetitive, high...

A Case Study of Ataxia Teilangiectasia Associated with Hodgkin Diease

A case of ataxia telangiectasia in a 7 year-old boy associated with Hodgkin disease was presented. Abnormalities of motion along with repeated respiratory tract infections requiring hospitalization started when he was 2 years old. The patient was placed on MOPP protocol Hodgkin treatment in addition to replace­ment therapy as advised.